Quiz Assertion (A) : In Thalassemia an abnormal myoglobin chain is synthesized due...
Question :Assertion (A) : In Thalassemia an abnormal myoglobin chain is synthesized due to a gene defect. Reason (R) : a-Thalassemia is controlled by genes HBA1 and HBA2 on chromosomé 16.
The correct answer is -The Assertion (A) is not correct, but the Reason (R) is correct.
Thalassemia is a group of genetic blood disorders that are characterized by reduced or absent synthesis of one or more of the globin chains of hemoglobin. It is not related to myoglobin, which is a protein found in muscle tissue that is involved in oxygen storage.
The Reason (R) is correct. Alpha thalassemia is caused by mutations in the HBA1 and HBA2 genes located on chromosome 16, which encode the alpha globin chains of hemoglobin. These mutations can lead to reduced or absent synthesis of alpha globin chains, resulting in the formation of abnormal hemoglobin molecules and a range of clinical symptoms.
Therefore, the Assertion (A) is not correct, but the Reason (R) is correct.
