5. Manisha Koirala

From being a superstar to being an alcoholic and battling cancer, Manisha Koirala has gone through several ups and downs in life. Koirala also suffered from clinical depression because of her personal relationship with her ex-husband Samrat Dahla. It is assumed that relationship troubles were the main cause which led to depression in Koirala’s case. However, Koirala battled against all odds and emerged victorious as she worked on herself and her psychological well being. Now, she is a healthy and strong woman.