Question: List the operational guidelines that must be adhered to so as to achieve optimisation of the bioreactor system. Enlist any four.
The correct answer is –
Sure, here are four operational guidelines that must be adhered to for achieving optimization of the bioreactor system:
- Monitoring and control of key parameters: In order to achieve optimal growth and productivity of the biological system, it is essential to monitor and control key parameters such as temperature, pH, dissolved oxygen, and nutrient levels. This can be achieved by using sensors and control systems that can adjust these parameters as needed.
- Optimization of mixing and aeration: Proper mixing and aeration are essential for ensuring uniform distribution of nutrients and oxygen to the biological system. The mixing and aeration rate should be optimized based on the specific requirements of the system, as well as the characteristics of the bioreactor being used.
- Minimizing contamination: Contamination can have a significant impact on the productivity of the biological system, so it is essential to minimize the risk of contamination by maintaining aseptic conditions throughout the process. This can be achieved by using sterile equipment, air filtration systems, and other appropriate measures.
- Maintenance and cleaning of the bioreactor: Regular maintenance and cleaning of the bioreactor are essential for ensuring optimal performance and longevity of the system. This includes routine inspection of the system, cleaning of all components, and replacement of any worn or damaged parts as needed.
