1 (i). Zara is suffering from cough and has bluish lips. Her mucus is mixed with
blood. What is the biological name of the causative organism responsible for Zara’s
condition?
Correct Answer: Mycobacterium tuberculosis
1 (ii). Observe the relation between the first two words and complete the analogy.
Dengue : Aedes :: Plague : ?
Correct Answer: Rat flea (Xenopsylla cheopis)
1 (iii). If the number of chromosomes in the cells of the calyx is 16, how many
chromosomes will be formed in the endosperm after double fertilisation?
Correct Answer: 24
1 (iv). A scientist isolates a second restriction endonuclease from the strain DC3
of Helicobacter pyogenes. What would the scientist name it using the standard
naming technique of restriction enzyme?
Correct Answer: H pyDC3II
1 (v). Meenu is suffering from a genetic disorder in which phenylpyruvic acid
and its metabolites accumulate in blood. It causes impairment of nervous tissues.
Which enzyme deficiency has caused this disorder in Meenu?
Correct Answer: Phenylalanine hydroxylase
1 (vi). There were 770 frogs in a pond. 70 of them died within a month. Calculate
the death rate of the population of frogs in the pond.
Correct Answer: 70/770 = 0.091 (approximately) or 9.09%
v1 (vii). A farmer notices that the leaves of his cabbage plants are curling up
because of heavy infestation of aphids. Suggest one ecofriendly method to control
their spread in the cabbage plants.
Correct Answer: Use biological control such as releasing ladybird beetles (predators of
aphids).
1 (viii). In a particular plant with bilobed dithecous anther, there were 50 Pollen
Mother Cells. Only 25% could develop their pollen tubes. Calculate the number
of pollen grains that would proceed for fertilisation.
Correct Answer: 50 pollen grains
1 (ix). Choose the components that are required for the proper functioning of
DNA polymerase enzyme.
• (P) DNA template
• (Q) A DNA primer
• (R) An RNA primer
• (S) Four different dNTPs
(a) Only (P), (Q) and (R)
(b) Only (P), (R) and (S)
(c) Only (Q), (R) and (S)
(d) Only (P), (Q) and (S)
Correct Answer: (b) Only (P), (R) and (S)
1 (x). The left hind limb of a person was swollen like an elephant’s limb. Which
one of the following was MOST likely the cause of swelling?
(a) Accumulation of uric acid
(b) Blockage of blood vessels
(c) Blockage of lymph vessels
(d) Hypertrophy of skeletal muscles
Correct Answer: (c) Blockage of lymph vessels
1 (xi). Given below are two statements marked Assertion and Reason. Read the
two statements carefully and choose the correct option.
Assertion: RNAi technique is applied to plants and animals to protect them from pest infestation.
Reason: This technique inhibits the expression of certain genes in pests.
(a) Both Assertion and Reason are true and Reason is the correct explanation for Assertion.
(b) Both Assertion and Reason are true but Reason is not the correct explanation for Assertion.
(c) Assertion is true and Reason is false.
(d) Both Assertion and Reason are false.
Correct Answer: (a) Both Assertion and Reason are true and Reason is the correct explanation for Assertion.
1 (xii). Given below are two statements marked Assertion and Reason. Read the
two statements carefully and choose the correct option.
Assertion: Individuals with Klinefelter syndrome lose their secondary sexual characters and
develop gynaecomastia.
Reason: The presence of the XYY chromosomal pattern leads to underdeveloped testes and
reduced testosterone levels in affected males.
(a) Both Assertion and Reason are true and Reason is the correct explanation for Assertion.
(b) Both Assertion and Reason are true but Reason is not the correct explanation for Assertion.
(c) Assertion is true and Reason is false.
(d) Both Assertion and Reason are false.
Correct Answer: (c) Assertion is true and Reason is false.
1 (xiii). In a garden pea plant, the flowers are in axial (A) position. Find out
the proportion of flowers in terminal position (a), if a cross is made between two
heterozygous plants.
Correct Answer: 1/4 or 25%
1 (xiv). Name the autoimmune disorder that affects the skeletal muscles in humans
Correct Answer: Myasthenia gravis
1 (xv). Answer the following:
(a) Expand the abbreviation IUI.
(b) The enzyme polynucleotide phosphorylase helps the in-vitro synthesis of RNA.
Name the scientist who discovered this enzyme.
Correct Answer: (a) Intrauterine Insemination (b) Severo Ochoa
1 (xvi). Shama complained of severe itching in certain parts of her body where
patches as shown below appeared on her skin. Write the biological name of the
causative agent responsible for her condition.
Correct Answer: Trichophytona
1 (xvii). Name the chemical messenger that activates Natural Killer T-cells and
macrophages.
SCorrect Answer: Interferon-γ (IFN-γ)
1 (xviii). Give a reason for each of the following:
(a) Kanika was suffering from SCID and needed periodic infusion of transformed
lymphocytes.
(b) In HIV infected persons, the immune system is compromised.
Solution:
Concept: Certain diseases affect the immune system and reduce the body’s ability to fight
infections.
(a) SCID (Severe Combined Immunodeficiency)
Step 1: Understand the disorder.
SCID is a genetic disorder in which the body fails to produce functional T-lymphocytes and
B-lymphocytes.
Step 2: Due to this deficiency, the immune system becomes extremely weak and cannot defend
the body against infections.
Step 3: Therefore, patients require periodic infusion of genetically transformed lymphocytes to restore immune function.
Reason: Because SCID patients lack functional lymphocytes, transformed lymphocytes are
infused to help build immune defense.
(b) HIV infection
Step 1: The Human Immunodeficiency Virus (HIV) specifically infects and destroys
CD4+ helper T-lymphocytes.
Step 2: These cells play a crucial role in coordinating immune responses.
Step 3: As the number of helper T-cells decreases, the immune system becomes weak and
unable to fight infections.
Reason: In HIV infection, destruction of CD4+ T-cells leads to weakening of the immune
system.
Question 2. The diagram below shows DNA banding patterns obtained after DNA
samples collected from a crime scene were subjected to gel electrophoresis. Samples
from the crime scene are denoted by C and three suspects are represented by S1,
S2, S3.
(i) Which suspect’s DNA sample matches the sample collected from the crime
scene?
(ii) Mention the principle on which DNA profiling is based.
Correct Answer: (i) S2 (ii) DNA profiling is based on DNA polymorphism in VNTR (Variable
Number Tandem Repeats).
Question 3. In a group discussion on pollination, Shubham argued that Cleistogamy
was a type of Xenogamy whereas Ameena was of the opinion that it was a kind of
Autogamy. Whose argument is correct? Justify.
Correct Answer: Ameena is correct.
Question 4. (i) The amount of energy at the fourth trophic level in the food chain
given below is 4 J.
Grass → Zebra → Crocodile → Vulture
What will be the amount of energy available at the sunlight and transducer level?
Correct Answer: Energy at producer (transducer) level = 4000 J Energy at sunlight level=4,00,000 J
(ii) Roselin had an aquarium at her home with 10 fish in it. In a year, a fish
gave birth to 7 fish. During this period, 3 adult fish had died. Roselin’s father
purchased 2 more pairs of fish from the market for the aquarium. Later, Roselin
gifted 4 fish from the aquarium to her friend. Find out the growth rate of fish in
Roselin’s aquarium.
Correct Answer: Growth rate = 4 fish per year
Question 5. Anthony is a scientist who has been provided with raw materials to
obtain a specific biological product in large quantities. His laboratory has two large
vessels for this purpose – one with a sparger and the other vessel with a stirrer.
Which vessel will be more advantageous to Anthony? Why?
Correct Answer: The vessel with a sparger (bioreactor) will be more advantageous.
Question 6. The data given below shows a significant decline in the population of
migratory birds in a wetland in Southern India over the last three years.
| Year |
Population of Birds |
Aquatic Plants (%) |
Aquatic Area (ha) |
| 2023 |
10,000 |
85 |
350 |
| 2024 |
8,000 |
60 |
280 |
| 2025 |
5,000 |
45 |
220 |
Based on the above data, interpret two reasons for change in the population of
migratory birds.
Solution:
Concept: Migratory birds depend heavily on wetlands for food, shelter, and breeding. Any
decline in habitat quality or availability of food resources can lead to a decrease in their population.
Step 1: Observe the trend in aquatic plants.
The percentage of aquatic plants has decreased from:
85% → 60% → 45%
Aquatic plants provide food and shelter for many aquatic organisms that serve as food for
migratory birds. Reduction in aquatic vegetation leads to a decline in food availability.
Reason 1: Decrease in aquatic plant cover has reduced food resources and habitat for
migratory birds.
Step 2: The aquatic area of the wetland has also decreased:
350 ha → 280 ha → 220 ha
This indicates shrinkage of the wetland habitat.
Reason 2: Reduction in wetland area has decreased the available habitat for migratory
birds.
Thus, the decline in bird population is mainly due to:
• Decrease in aquatic plant cover
• Reduction in wetland (aquatic) area
Question 7. Paramecium caudatum and Paramecium aurelia were growing in
separate culture media in a laboratory. When both the species were transferred to
the same culture medium for growth, it was observed that Paramecium caudatum
got eliminated from the habitat after some time. Identify and explain the type
of ecological interaction between the aforementioned species of Paramecia on the
basis of Gause’s principle.
Correct Answer: Interspecific competition (Competitive exclusion principle).
Question 8. In an experiment to produce recombinant cells, a plasmid without
selectable marker was chosen as the vector for cloning a gene.
(i) Predict the outcome of this experiment.
(ii) Name an artificial chromosome that can be used as a vector to transfer the
recombinant DNA in Penicillium notatum.
Correct Answer: (i) Recombinant cells cannot be easily identified or selected. (ii) Yeast
Artificial Chromosome (YAC).
Question 9. (i) How is mature insulin different from pro-insulin secreted by pancreas in humans?
(ii) Name the company that produced genetically engineered insulin for the first
time.
(iii) Why is functional insulin produced by r-DNA technology better than the ones
produced earlier?
Correct Answer:
• (i) Mature insulin contains only A and B chains, while pro-insulin contains an additional
C-peptide.
• (ii) Eli Lilly
• (iii) Recombinant insulin is highly pure, safe, and does not cause allergic reactions like
earlier animal-derived insulin.
Question 10. A biologist surveyed islands of different sizes and consolidated the
results in the form of the data given below. Study the data carefully and answer
the questions that follow.
| Name of Islands |
Island Area (sq. km) |
No. of mammalian species |
| P |
1 |
5 |
| Q |
10 |
18 |
| R |
100 |
60 |
| S |
1000 |
150 |
(i) What pattern do you observe in the above data?
(ii) Name the scientist who proposed the concept of relationship between area and
species.
(iii) Write the mathematical expression for this relationship.
Correct Answer:
• (i) As the island area increases, the number of species also increases.
• (ii) Alexander von Humboldt
• (iii) S = CAZ
Question 11. (i) Draw a flowchart to show the process of sex determination in
honeybees.
(ii) If there are 16 chromosomes in the somatic cells of a male honeybee, how many
chromosomes would be present in spermatozoa?
Correct Answer:
• (i) Sex determination in honeybees follows the haplodiploid mechanism.
• (ii) 16 chromosomes
Question 12. Study the chemical structure of an addictive drug shown below and
answer the questions that follow.
(i) Mention the scientific name of the source plant of the above drug.
(ii) State any one effect of this drug on human body.
(iii) What is meant by withdrawal symptom?
Correct Answer:
• (i) Cannabis sativa
• (ii) It affects the central nervous system and may cause hallucinations or impaired coordination.
• (iii) Withdrawal symptoms are unpleasant physical or psychological effects experienced
when a person stops taking an addictive drug.
Question 13. A researcher compares two embryos, X and Y.
• Embryo X shows equal division of the zygote, forming two cells that are almost identical
in size.
• Embryo Y shows an unequal first division and produces a small apical cell and a large
basal cell.
(i) Which embryo is likely to develop into a normal dicot embryo?
(ii) What is the fate of:
(a) Apical cell?
(b) Basal cell?
Correct Answer:
• (i) Embryo Y
• (ii)
– (a) Apical cell forms the embryo proper.
– (b) Basal cell forms the suspensor.
Question 14. (i) The graph given below shows the level of antibodies in the blood
after exposure to a pathogen.
(a) What types of responses of the immune system do the peaks A and B represent?
(b) Name the type of antibody that is at the highest level in the 7th week.
Correct Answer:
• (a) Peak A – Primary immune response; Peak B – Secondary immune response.
• (b) IgG
(ii) Plasmodium is a digenetic parasite, completing its life cycle in humans and
mosquitoes. In humans, it completes different parts of its life cycle in the liver and
RBCs. Draw a flow chart to outline its erythrocytic cycle in humans.
Solution:
Concept: The erythrocytic cycle of Plasmodium occurs in the red blood cells of humans.
During this stage, the parasite multiplies inside RBCs and causes their rupture, leading to the
characteristic symptoms of malaria.
Flow chart of erythrocytic cycle:
Merozoites released from liver → Enter RBCs
→ Trophozoite stage (feeding stage)
→ Schizont stage (multiple nuclear divisions)
→ Formation of many merozoites
→ Rupture of RBC
→ Release of merozoites and toxins
→ Invasion of new RBCs
This cycle repeats and leads to the periodic fever observed in malaria.
Question 15. The two structures shown below are formed in the process of spermatogenesis. Study them carefully and answer the questions that follow.
(i) Identify the process which converts Structure A to Structure B.
(ii) State any two modifications observable in Structure B.
Correct Answer:
• (i) Spermiogenesis
• (ii)
– Formation of a flagellum (tail) for motility.
– Development of an acrosome on the head of the sperm.
Question 16. As a part of his research, Arun conducted a study on the number of
locusts in a forest. He compiled his findings in the form of the following data.
| Day |
Number of locusts |
| 1 |
5 |
| 2 |
10 |
| 5 |
25 |
| 10 |
50 |
| 15 |
105 |
| 20 |
170 |
| 25 |
280 |
| 30 |
360 |
| 35 |
200 |
(i) Construct a growth curve based on the above data. What type of a growth
curve is obtained?
(ii) Write a mathematical expression for the growth curve obtained
Correct Answer:
• (i) Sigmoid (S-shaped) growth curve / Logistic growth curve.
• (ii) dN/dt = rN (
K − N/K
)
Question 17. Study the diagram given below and answer the questions that follow.
(i) Identify the parts marked ‘E’ and ‘F’.
(ii) Explain the post-transcriptional modifications that occur in part ‘F’.
Correct Answer:
• (i) E – Promoter region ; F – Primary RNA transcript (hnRNA / pre-mRNA)
• (ii) Post-transcriptional modifications include capping, tailing and splicing
Question 18. (i) Outline three major steps in the process of artificial hybridisation.
(ii) Discuss the role of pollen–pistil interaction in ensuring successful hybrid formation.
OR
(iii) Draw a flowchart to represent the process of oogenesis.
(iv) Differentiate between oogenesis and spermatogenesis on the following basis:
(a) Number of products
(b) Gonadal hormones
Solution:
(i) Major steps in artificial hybridisation
Concept: Artificial hybridisation is a plant breeding technique in which pollen from a selected
male parent is manually transferred to the stigma of a chosen female parent to obtain desired
hybrids.
Steps:
• Emasculation: Removal of anthers from a bisexual flower before they release pollen to
prevent self-pollination.
• Bagging: The emasculated flower is covered with a suitable bag to prevent contamination
from unwanted pollen.
• Artificial Pollination: Pollen grains from the desired male parent are dusted onto the
stigma of the female flower and the flower is again bagged.
(ii) Role of pollen–pistil interaction
Concept: Pollen–pistil interaction refers to the series of events that occur from the time pollen
lands on the stigma until fertilisation occurs.
• The stigma recognises whether the pollen is compatible or incompatible.
• Compatible pollen grains germinate on the stigma and produce pollen tubes.
• The pollen tube grows through the style and reaches the ovule.
• This interaction ensures that only the correct pollen fertilises the ovule, leading to successful hybrid formation.
OR
(iii) Flowchart of oogenesis
(iv) Difference between oogenesis and spermatogenesis
| Basis |
Oogenesis |
Spermatogenesis |
| Number of products |
One ovum and three polar bodies |
Four functional sperms |
| Gonadal hormones |
Estrogen and progesterone |
Testosterone |
CBSE 12th and 10th Syllabus and Model Papers
Last Updated on : March 26, 2026