After Jamakhandi merged with Bombay state in 1948, B D Jatti became the nominated member of the merged state in the Bombay State Legislative Assembly. In the same week he was appointed as a Parliamentary Secretary to the Chief Minister of Bombay, Mr B.G.Kher. After serving for two years as the private secretary to the Bombay Chief Minister, B D Jatti was appointed as the Deputy Minister for Health and Labor. After that B D Jatti was appointed as the chairman of Land Reforms Committee in the Mysore Legislative Assembly. In 1958 he was elected as the Chief Minister of Mysore and continued in this position till 1962. In the third general elections in 1962, he was re-elected from Jamkhandi constituency and appointed as Finance Minister in the Nijalingappa Ministry.
B D Jatti came to the national scene in 1968 when he became the Lt Governor of Pondicherry. After a period of five years, in 1973, he was appointed as the Governor of Orissa. The subsequent year in 1974, B D Jatti moved to New Delhi to assume the office of the Vice-President of India. He was also the ex- officio Chairman, Rajya Sabha till 1979. He also held the Office of the President Of India for a brief period of 5 months from February 11, 1977 to July 25, 1977 due to the sudden death of Fakruddin Ali Ahmed, the then President of India. He passed away on 8th June 2002.